Rheumatoid arthritis notes.pdf

Rheumatoid arthritis

Introduction
 Rheumatoid arthritis is an autoimmune disorder that causes
symmetrical polyarthritis.
 Arthritis is an inflammation of the joints.
 Rheumatoid arthritis awareness day celebrated on 2nd Feb.
 Rheumatoid arthritis is a most common systemic inflammatory disease
characterized by symmetrical joint involvement.

Definition
 Rheumatoid arthritis is a chronic autoimmune disorder that include
inflammation in the membrane lining of the joint and produce an
inflammatory synovitis.
 Rheumatoid arthritis generally involves small, peripheral and systemic
or non-weight wear joints.
 Commonly prevalence between the age of 30 - 50 years.

Cause
 Idiopathic
 Genetic factors
 Environmental exposure
 Immunological factor
 Autoimmune disorder
 Endocrine imbalance
 Inflamed synovium
 Tumour necrosis factor
 DM, obesity