Emphysema Notes Download.pdf

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Published March 31, 2025
Updated March 31, 2025

Emphysema

Definition
 Emphysema is defined as impaired gas exchange resulting from the
destruction of the wall of alveoli.
 Emphysema is abnormal permanent air space enlargement distal
to the terminal bronchioles.
 Emphysema is a chronic, progressive disease of the lungs and occurs
when the alveolar walls are destroyed.
 Emphysema is a type of COPD, including excessive air in the terminal
bronchioles.

Types of Emphysema
1. Centrilobular emphysema - Emphysema mainly in the centre of
secondary lobules.

2. Pan lobular emphysema - It is a permanent destruction of the
entire acinus distal to the respiratory bronchioles.

3. Distal acinar emphysema - distal part of acinus is involved.

4. Irregular emphysema - The acini are irregularly involved.

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